Sulphanilamide Eruption

Herpes Zoster and Sulphanilamide

For cutting short the severe pain and the course of herpes zoster, apart from big doses of analgesics, oral administration of sodium iodide, injection of pituitary extract and even ultraviolet radiation therapy have all been tried with little good result. In April 1938, Maplestone and Ghose advocated intradermal injection of tissue-lysate, prepared from the herpetic vesicles, and according to t...

On Soluble Sulphanilamide Derivatives

In any sulphanilamide therapy, it is the concentration of the drug in blood that determines its therapeutic efficacy. The amount of the drug itself in the circulating blood should always be determined by actual quantitative estimation (Hansen, 1939). Under ordinary conditions sulphanilamide taken by mouth is rapidly absorbed from the gastro-intestinal tract and is found in practically all the b...

Sulphanilamide: The Second Phase

Sulphanilamide in Treatment

considerably less toxic than sulphanilamide, and equally effective, at least as regards streptococci. Both drugs are supposed to act directly on the cocci, rendering their capsules more permeable, or at least iess protective. The dose of either for an adult is two or three half-gram tablets by mouth thrice daily, though this is often considerably exceeded. Children tolerate proportionate doses ...

Sulphanilamide in Acute Nephritis